84-2409-72　［取扱停止］TXA Synthase (BDPLT14, CYP5, CYP5A1, Cytochrome P450 5A1, Cytochrome P450, Family 5, SubFamily A, Polypeptide 1, FLJ52771, GHOSAL, Platelet cytochrome P450 SubFamily V, TBXAS1, THAS, THAS_HUMAN, Thromboxane A Synthase 1 (platelet), Thromboxane A Synthase 1 (platelet, cytochrome P450, Family 5, SubFamily A), Thromboxane A Synthase 1, Thromboxane A Synthase 1 platel ...　226531

特徴

• TXA synthase, also referred to as thromboxane synthase or CYP5, is an enzyme that catalyzes the conversion of the prostaglandin endoperoxide (PGH2) into Thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation.
• TXA synthase is an important part of the cytochrome P450 system.
• Thromboxane A2 plays a pivotal role in the maintenance of hemostasis and cardiovascular diseases along with Prostacyclin.
• The expression of TXA synthase has been found to be consistently upregulated in several types of cancer tissues suggesting the involvement of this enzyme in tumor growth in humans.
• Thromboxanes are produced by TXA synthase in excess in inflammatory bowel disease.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.