The transient receptor potential (TRP) protein family consists of a diverse group of cation channels functioning in a variety of homeostatic and regulatory pathways.
Four subfamilies exist, based on channel domain homology, not activating stimuli: C type (canonical or classical), V type (vanilloid receptor related), M type (melastatin related) and P type (PKD).
TRPV4, also designated VRL-2, TRP12, VR-OAC and OTRPC4, belongs to the V type subfamily, and plays a role in systemic osmoregulation.
TRPV4 is a calcium channel activated by various stimuli, including thermal stress, fatty acid metabolites and hypotonicity.
TRPV4 is highly expressed in lung and kidney.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of TRPV4. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant full length Human TRPV4.
Shelf Life：1year
Swiss Prot Number：Q9HBA0
EU Commodity Code：30021010
商品名：TRPV4 (osm 9 like TRP Channel 4, osm-9-like TRP Channel 4, OTRPC 4, OTRPC4, Transient Receptor potential cation Channel Subfamily V Member 4, Transient Receptor potential Protein 12, TRP 12, TRP12, TRPV 4, TrpV4, TRPV4_HUMAN, Vanilloid Receptor like Channel 2, Vanilloid Receptor like Protein 2, Vanilloid Receptor Related osmotically Activated Channel, Vanilloid Receptor-like Channel 2, Vanilloid Receptor-like Protein 2, Vanilloid Receptor-Related osmotically-Activated Channel, VR 4, VR OAC, VR-OAC, VR4, VRL 2, VRL-2, VRL2, VROAC) 50ul
