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84-2408-77 [取扱停止]TRPM2 (EREG 1, EREG1, Estrogen responsive Element Associated Gene 1, Estrogen responsive Element Associated Gene 1 Protein, Estrogen-responsive Element-Associated Gene 1 Protein, KNP 3, KNP3, Long transient Receptor potential Channel 2, LTRPC 2, LTrpC-2, LTRPC2, MGC133383, NUDT9H, NUDT9L1, putative Ca2+ Channel Protein, transient Receptor potential cation Channel ... 226480
84-2408-77 [取扱停止]TRPM2 (EREG 1, EREG1, Estrogen responsive Element Associated Gene 1, Estrogen responsive Element Associated Gene 1 Protein, Estrogen-responsive Element-Associated Gene 1 Protein, KNP 3, KNP3, Long transient Receptor potential Channel 2, LTRPC 2, LTrpC-2, LTRPC2, MGC133383, NUDT9H, NUDT9L1, putative Ca2+ Channel Protein, transient Receptor potential cation Channel ... 226480
特徴
- Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress.
- Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation.
- Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid.
- Inactivated by intracellular ATP.
- Confers susceptibility to cell death following oxidative stress.
- Isoform 2 does not seem to be regulated by ADPR.
- Has ADP-ribose pyrophosphatase activity.
- Applications:Suitable for use in Western Blot, Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:50ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
- Specificity:Recognizes endogenous levels of TRPM2. Species Crossreactivity: Human
- Isotype:IgG
- Calc Applications Abbrev:IHC WB
- Calc Crossreactivity:Hu
- Immunogen:Recombinant full length Human TRPM2.
- Shelf Life:1year
- Swiss Prot Number:O94759
- EU Commodity Code:30021010
- 商品名:TRPM2 (EREG 1, EREG1, Estrogen responsive Element Associated Gene 1, Estrogen responsive Element Associated Gene 1 Protein, Estrogen-responsive Element-Associated Gene 1 Protein, KNP 3, KNP3, Long transient Receptor potential Channel 2, LTRPC 2, LTrpC-2, LTRPC2, MGC133383, NUDT9H, NUDT9L1, putative Ca2+ Channel Protein, transient Receptor potential cation Channel Subfamily M Member 2, Transient Receptor potential Channel 7, TRPC 7, TRPC7, TRPM 2, Trpm2, TRPM2_HUMAN) 50ul
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