84-2408-29　［取扱停止］TRIM27 (Zinc Finger Protein RFP, RING Finger Protein 76, Ret Finger Protein, Tripartite Motif-Containing Protein 27, TRIM27, RFP, RNF76) 50ul　226454

特徴

• TRIM27, also designated Ret finger protein (RFP), is a member of the tripartite motif family, which is characterized by a conserved RING finger, a B-box and a coiled-coil domain (together designated RBCC).
• TRIM27 becomes oncogenic when its RBCC is fused with the tyrosine kinase domain of the RET protein.Normally, TRIM27 functions as a transcriptional repressor and associates with enhancer of polycomb (EPC1) and Mi-2beta, a main component of the nucleosome remodeling and deacetylase (NuRD) complex.
• TRIM27 is expressedat specific stages of spermatogenesis and in various tissues and can be localized to either the cytoplasm or nucleus depending on the cell type.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.