TRIM21 has multiple N-terminal zinc finger motifs(has E3 ligase activity), a central leucine zipper, and a potential N-glycosylation site.
TRIM3 is a E3 ubiquitin-protein ligase.
It can form a ubiquitin ligase complex with E2 UBE2D2, which function not only for the uniquitination of USP4 and IKBKB but also for its self-ubiquitination.
It has a role in the regulation of the cell cycle progression and could enhance the decapping activity of DCP2.
It can exist in all mammalian cells as a ribonucleoprotein particle , which composed of a single polypeptide and 1 of 4 small RNA molecules.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of TRIM21. Species Crossreactivity: Human
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant full length Human TRIM21.
Shelf Life：1year
Swiss Prot Number：P19474
EU Commodity Code：30021010
商品名：TRIM21 (52kD Ribonucleoprotein Autoantigen Ro/SS-A, 52kD Ro Protein, 52kD Ro/SSA Autoantigen, Autoantigen Ro/SSA, 52-KD, E3 Ubiquitin-Protein Ligase TRIM21, RING Finger Protein 81, RNF81, Ro 52, Ro(SS-A), Ro52, RO52_HUMAN, Sicca Syndrome Antigen A, Sjoegren Syndrome Type A Antigen, Sjogren Syndrome Antigen A1, Sjogren Syndrome Type A Antigen, SS-A, SSA, SSA1: Sjogren Syndrome Antigen A1 (52kDa Ribonucleoprotein Autoantigen SS-A/Ro), TRIM21, Tripartite Motif Protein TRIM21, Tripartite Motif-Containing 21, Tripartite Motif-Containing Protein 21,) 100ul
