84-2408-25　［取扱停止］TRIM13 (B Cell chronic lymphocytic Leukemia Tumor Suppressor Leu5, B-Cell chronic lymphocytic Leukemia Tumor Suppressor Leu5, CAR, DLEU5, E3 Ubiquitin-Protein Ligase TRIM13, HGNC:9976, LEU5, Leukemia Associated Protein 5, Leukemia-Associated Protein 5, Putative Tumor Suppressor RFP2, Ret Finger Protein 2, RING Finger Protein 77, RNF77, TRI13_HUMAN, TRIM13, Tripart ...　226452

特徴

• The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B box-type zinc finger, one RING finger and three zinc-binding domains.
• Rfp2 (Ret finger protein 2), also known as TRIM13 (tripartite motif-containing 13), CAR, RNF77 or LEU5, is a 407 amino acid protein that belongs to the TRIM protein family and contains one B box-type zinc finger and one RING-type zinc finger.
• Existing as two alternatively spliced isoforms designated alpha and beta, Rfp2 is thought to act as a tumor suppressor that, when defective, may be involved in the development and progression of B-cell chronic lymphocytic leukemia.
• Additionally, Rfp2 may function as an E3 ubiquitin ligase that is involved in protein degradation pathways related to the ER-associated degradation (ERAD) pathway.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.