TNFalpha-IP 1 (tumor necrosis factor, alpha-induced protein 1, endothelial), also known as B12, B61, EDP1 or TNFAIP1, is a BTB/POZ domain-containing protein that belongs to the KCTD10/KCTD13/TNFAIP1 family.
TNFalpha-IP 1 contains one BTB/POZ motif, which is known to mediate homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling.
The expression of TNFalpha-IP 1 can be induced by IL-6 and by TNFalpha in the umbilical vein of endothelial cells.
TNFalpha-IP 1 may be involved in DNA repair, DNA synthesis, cell apoptosis and human diseases.
TNFalpha-IP 1 is suggested to play a role in the process of cancer and in the innate immunity against the Hepatitis B virus.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of TNF-IP. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 90-140 of Human TNF-IP 1.
