Proteins in the thymosin beta family are highly conserved polar peptides that bind monomeric Actin and thereby inhibit Actin polymerization.
These proteins act as the main intracellular G-Actin sequestering peptides.
The most abundant thymosin beta family member in mammalian cells and tissues is thymosin beta-4 (Tbeta-4), also designated Seraspenide.
Tbeta-4 participates in several cellular events including cancerogenesis, apoptosis, angiogenesis, blood coagulation and would healing.
Specifically, Tbeta-4 promotes cell migration and adhesion, accelerates wound healing and reduces inflammation, and becomes upregulated in a wide variety of human carcinomas.
Due to the effects of Tbeta-4 in these events, it may become a protein of significant biological and pharmaceutical relevance.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of TMSB4X. Species Crossreactivity: Human, mouse, rat
