The transcriptional enhancer factor (TEF)/TEAD family of proteins includes TEF-1, TEF-3, TEF-4 and TEF-5, all of which share a highly conserved 68 amino acid TEA/ATTS DNA-binding domain.
TEF-5 (transcriptional enhancer factor-5), also known as TEAD3, TEAD5, DTEF-1 or ETFR-1, is a 435 amino acid nuclear protein that contains one TEA DNA-binding domain and belongs to the TEF transcriptional enhancer family.
Expressed predominately in placental tissue and skeletal muscle, TEF-5 binds to multiple sites in the promotor of Placental lactogen II (also known as chorionic somatomammotropin-B) and, via this binding, enhances Placental lactogen II transcription.
Due to its ability to enhance the expression of placenta-related genes, TEF-5 is thought to function as an important regulatory protein within the human placenta.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of TEF-5. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 213-260 of Human TEF-5.
