The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC).
This complex consists of two identical stacked rings, each containing eight different proteins.
Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner.
The complex folds various proteins, including actin and tubulin.
Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.
In addition, three pseudogenes that appear to be derived from this gene have been found.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of TCP1. Species Crossreactivity: Human, mouse, rat
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Recombinant full length Human TCP1.
Shelf Life:1year
Swiss Prot Number:P17987
EU Commodity Code:30021010
商品名:TCP1 (AI528772, c-cpn, CCT alpha, CCT, CCT-alpha, CCT1, Ccta, CCTalpha, D6S230E, MGC133746, p63, T Complex 1, T Complex Protein 1 alpha Subunit, T Complex Protein 1, T-Complex Homolog TCP1, T-Complex Protein 1 Subunit alpha, T-Complex Protein 1 Subunit alpha B, Tailless Complex Polypeptide 1, Tailless Complex Polypeptide 1A, Tailless Complex Polypeptide 1B, TCP 1 alpha, Tcp-1, TCP-1-alpha, TCP1, TCPA_HUMAN, Tp63, TRic,) 50ul