84-2403-73　［取扱停止］TCEAL1 (TCEA-like Protein 1, TCEAL1, pp21, SIIR) 100ul　226223

特徴

• TCEAL1 (transcription elongation factor A (SII) protein 3), also known as p21, SIIR or pp21, is a member of the TFS-II family.
• Transcription elongation factors of the TFS-II family are responsible for releasing RNA polymerase II (Pol II) from transcriptional arrest.
• DNA arresting sites can result in locked ternary complexes if elongating RNA polymerases are trapped.
• Transcription elongation factors function to activate the intrinsic RNA cleavage activity of RNA polymerases.
• This allows the RNA polymerase to cleave the nascent transcript, thereby forming a new 3’-terminus to resume elongation.
• TCEAL1 is a 157 amino acid nuclear protein that is ubiquitously expressed.
• TCEAL1 may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.