84-2402-62　［取扱停止］TADA3L (ADA3, ADA3 Homolog, ADA3-like Protein, FLJ20221, FLJ21329, hADA3, Transcriptional adaptor 3 (NGG1 Homolog yeast) like, Transcriptional adaptor 3 like,) 100ul　226166

特徴

• ADA3 (Transcriptional adapter 3-like, STAF54) is a 432 amino acid protein encoded by the human gene TADA3L.
• ADA3 is a ubiquitously expressed nuclear protein that functions as a component of the PCAF (p300/CBP-associated factor) complex.
• The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context.
• The PCAF complex is the human homolog of the yeast SAGA complex.
• ADA3 interacts with the E6 gene and is a target of E6-induced degradation.
• ADA3 binds selectively to the high-risk HPV E6 proteins and immortalization-competent E6 mutants.
• ADA3 functions as a coactivator for p53-mediated transactivation by stabilizing p53 protein.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.