The tachykinin family consists of amidated neuropeptides that share a carboxy-terminal sequence (Phe-X-Gly-Leu-Met-NH2).
Tachykinin peptides have many plieotropic functions including: neurotransmission, immune/hematopoietic modulation, angiogenesis and mitogenesis.
Neurokinin B (NKB), also known as TAC3 (tachykinin 3), NKNB or ZNEUROK1, is a 121 amino acid secreted protein that belongs to the tachykinin family and exists as three alternatively spliced isoforms.
Expressed primarily in the central and peripheral nervous system, Neurokinin B is also found in the placental outer syncytiotrophoblast and is thought to have a role in pregnancy-induced pre-eclampsia and hypertension.
The gene encoding Neurokinin B maps to human chromosome 12, which comprises ~4.5% of the human genome.
Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of TAC3. Species Crossreactivity: Human
