84-2402-50　［取扱停止］TAC1 (Protachykinin-1, PPT, Substance P, Neurokinin A, NKA, Neuromedin L, Substance K, Neuropeptide K, NPK ,Neuropeptide gamma, C-Terminal-flanking peptide, TAC1, NKA, NKNA, TAC2) 100ul　226160

特徴

• The tachykinin familyconsists of amidated neuropeptidesthatshare a carboxyterminalsequence (Phe-X-Gly-Leu-Met-NH2).
• Preprotachykinin I, also designated protachykinin 1 precursor (PPT), is a common precursor of tachykinins.
• Preprotachykinin I alternatelysplicesto formvariousisoforms.
• These isoforms include: Substance P; Neurokinin A (NKA, Substance K, Neuromedin L); Neurokinin B;Neuropeptide K (NPK);Neuropeptide y; and C-terminal flanking peptide.
• Substance P is expressesed primarilyin the small diameter primary sensoryfibers of the peripheral nervoussystem, and in the superficial dorsal horn of the spinalcord, the substantia nigra, and the medial amygdaloid nucleus of the central nervoussystem.
• Tachykinin peptides havemany plieotropicfunctionsincluding: neurotransmission, immune/ hematopoieticmodulation, angiogenesis andmitogenesis.
• Preprotachykinin I has been implicated in breastcancer and bonemarrowmetastasis.
• Substance P plays a role in depression.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.