84-2401-69　［取扱停止］SUMO4 (dJ281H8.4, IDDM5, Small Ubiquitin like modifier 4 Protein, Small Ubiquitin-like Protein 4, Small Ubiquitin-Related modifier 4, SMT3 Suppressor of mif two 3 Homolog 2, SMT3 Suppressor of mif two 3 Homolog 4 (S. cerevisiae), SMT3H4, SUMO 4, SUMO-4, SUMO4, SUMO4_HUMAN,) 100ul　226117

特徴

• This gene is a member of the SUMO gene family.
• This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity.
• The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene.
• A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes.
• The RefSeq contains this polymorphism.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.