84-2401-52　［取扱停止］SULT1A1 (Aryl Sulfotransferase 1, HAST1/HAST2, Human aryl Sulfotransferase mRNA complete cds, MGC131921, MGC5163, OTTHUMP00000162568, OTTHUMP00000162569, P PST 1, P PST, P-PST 1, Phenol sulfating phenol Sulfotransferase 1, Phenol Sulfotransferase 1, Phenol-sulfating phenol Sulfotransferase 1, PST, ST1A1, ST1A1, ST1A3, STP, STP1, Sulfotransferase 1A1, Sulfotransfer ...　226109

特徴

• The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances.
• Members of the three groups comprising this superfamily (namely SULT1, SULT2 and SULT3) show selectivity to certain substrate compounds.
• SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid protein that localizes to the cytoplasm and belongs to the sulfotransferase family.
• Functioning as a homodimer that is expressed in brain, liver, skin and lung tissue, SULT1A1 catalyzes the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters and, via this catalytic activity, plays a role in the elimination of a variety of compounds from the body.
• Additionally, SULT1A1 may be involved in the activation of carcinogenic N-hydroxyarylamines, indicating a possible role in carcinogenesis.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.