SCG10, also designated stathmin-like 2 (STMN2), is a neuronal growth-associated protein (nGAP) that belongs to the stathmin family.
Stathmin family phosphoproteins are involved in regulation of microtubule dynamics and signal transduction.
SCG10, which is membrane- associated and neuron-specific, may participate in neuronal differentiation and may modulate membrane interaction with the cytoskeleton during neurite outgrowth.
The SCG10 protein binds to and inhibits the assembly of microtubules, and can also induce microtubule disassembly.
The assembly and disassembly of microtubules is necessary for cell division, intracellular transport and cell movements, as well as neurite elongation, outgrowth and branching in the developing nervous system.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of STMN2. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 134-179 of Human STMN2.
