Protein kinases catalyze the post-translational transfer of a phosphate group from ATP to a serine, threonine or tyrosine residue, thereby playing a major role in many intracellular and intercellular signaling cascades.
STK31 (Serine/threonine-protein kinase 31) is a 1019 amino acid protein belonging to the protein kinase superfamily.
STK31 contains one C-terminal protein kinase domain and one N-terminal Tudor domain, which functions as a protein-protein interaction motif during RNA metabolism or transport.
As a testis-specific kinase, STK31 is found in both post-meitoic spermatocytes as well as in mature spermatozoa and is thought to be involved in spermatogensis and/or sperm function.
Also, as a result of frequent expression in colorectal, gastric and esophageal cancers, STK31 has been identified as a potential cancer/testis (CT) antigen.
There are two named isoforms of STK31 which are produced as a result of an alternative splicing event.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of STK31. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to residues in Human STK31.
