Stromalins are a group of highly conserved proteins that are characterized by the stromalin conservative domain.
Stromal antigen 3 (STAG3) is a nuclear protein that is expressed specifically in germinal cells.
STAG3 associates with the synaptonemal complex (SC) via immunolocalization.
The SC is a meiotic protein structure that aids in the pairing of homologous chromosomes.
In mammals, STAG3 associates with the SC and assists in sister chromatid cohesion, which keeps the homologous chromosomes appropriately aligned during the pachytene stage of prophase I.
STAG3 appears to be located at the interchromatid domain during metaphase I, but is undetectable in ana-phase I or any of the later stages of meiosis.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, pH 7.2, 0.05% sodium azide
Specificity：Recognizes endogenous levels of human STAG3.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 1156-1200 of human STAG3.
