84-2400-07　［取扱停止］SSB (Autoantigen La, La, La Autoantigen, La Autoantigen Homolog, La Protein, La Ribonucleoprotein, La Ribonucleoprotein Domain Family Member 3, LA, LARP3, Lupus La Antigen, Lupus La Protein, Lupus La Protein Homolog, MGC118101, MGC93380, mRNA for Autoantigen, OTTMUSP00000014043, RP23 273G23.1, Sjoegren Syndrome Type B Antigen, Sjoegren Syndrome Type B Antigen, Sjo ...　226036

特徴

• Ro/SSA is a ribonucleoprotein that binds to autoantibodies in 35 to 50% of patients with SLE and in up to 97% of patients with Sjogren syndrome.
• The Ro/SSA particle consists of a single immunoreactive protein noncovalently bound with one of four small RNA molecules.
• Most anti-Ro/SSA-positive sera have antibodies not only against the immunoreactive protein, but also against an Ro/SSA protein.
• The genes which encode the two proteins map to human chromosomes 11p15.5 and 1q31, respectively.
• La/SSB is an autoimmune RNA-binding protein that plays a role in the transcription of RNA polymerase III was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and SLE.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.