Over 100 cell surface markers have been identified through the use of monoclonal antibodies.
Many of these markers have proven useful in identifying a specific subpopulation of cells within a mixed colony.
Accordingly, these molecules have been assigned a “cluster of differentiation” (CD) designation.
CD43 is the major O-glycosylated cell-surface associated sialoglycoprotein found on the cell membranes of leukocytes.
It is a member of the surface mucin family which plays a central role in cellular adhesion tumor progression.
Also called leukosialin, CD43 is best known as a marker for identifying normal and neoplastic T cells and a subset of neoplastic B cells within tissues.
CD43 is thought to function as a negative regulator of cellular adhesion.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of SPN. Species Crossreactivity: Human