Eppin, an epididymal protease inhibitor, belongs to the WFDC family and to the telomeric cluster.
The gene encoding the protein is localized to chromosome 20q12-q13 in centromeric and telomeric clusters.
It expresses three mRNAs encoding two isoforms of a cystine-rich protein that contains Kunitz-type and WAP-type (four disulfide core) protease inhibitor consensus sequences.
The mouse gene lies in a cluster of putative Eppin-like genes on mouse chromosome 2.
Following ejaculation, Eppin is bound to semenogelin in seminal plasma and on human spermatozoa.
This complex of Eppin and Semenogelin can provide antimicrobial activity for spermatozoa.
It can also provide for the preparation and survival of spermatozoa for fertility in the female reproductive tract.
Eppin, which is a secreted protein, is expressed in epididymis and testis.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of SPINLW1. Species Crossreactivity: Human
