Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY.
These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity.
Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes.
The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages.
At present, 30 Sox genes have been identified.
Members of this family have been shown to be conserved during evolution and to play key roles during animal development.
Some are involved in human diseases, including sex reversal.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of SOX9, phosphorylated S181. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic phosphopeptide derived from human SOX9 around the phosphorylation site of Serine 181.
