Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes.
The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages.
At present, 30 Sox genes have been identified.
Members of this family have been conserved during evolution and play key roles during animal development.
Some are involved in human diseases, including sex reversal.
Sox-11 (SRy (sex determining region y)-box 11) is a 441 amino acid nuclear protein expressed mainly in the nervous system.
Containing an HMG box DNA-binding domain, Sox-11 may play a critical role in the developing nervous system.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of SOX11. Species Crossreactivity: Human, mouse
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：A synthetic peptide corresponding to residues in Human SOX11.
