84-2398-55　［取扱停止］SNX9 (MST 155, MST155, MSTP 155, MSTP155, OTTHUMP00000040083, Protein SDP 1, Protein SDP1, SDP 1, SDP1, SH3 and PX Domain Containing Protein 3A, SH3 and PX Domain Containing Protein SH3PX1, SH3 and PX Domain-Containing Protein 1, SH3 and PX Domain-Containing Protein 3A, SH3PX1, SH3PXD3A, SNX 9, SNX9, SNX9, Sorting nexin 9, Sorting nexin-9, WASP Interactor Protein, ...　225960

特徴

• May be involved in several stages of intracellular trafficking.
• Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis.
• Plays a role in macropinocytosis.
• Promotes internalization of TNFR.
• Promotes degradation of EGFR after EGF signaling.
• Stimulates the GTPase activity of DNM1.
• Promotes DNM1 oligomerization.
• Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton.
• Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation.
• Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.