The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin.
The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome.
The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex.
Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of SMARCE1. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant full length Human SMARCE1.
Shelf Life：1year
Swiss Prot Number：Q969G3
EU Commodity Code：30021010
商品名：SMARCE1 (BAF57, BRG1 Associated Factor 57, BRG1-Associated Factor 57, Chromatin remodeling Complex BRG1 Associated Factor 57, FLJ35648, SMARCE 1, SMARCE1, SMCE1_HUMAN, SWI/SNF Related Matrix Associated Actin Dependent Regulator of chromatin e1, SWI/SNF Related Matrix Associated Actin Dependent Regulator of chromatin Subfamily e Member 1, SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator of chromatin Subfamily E Member 1,) 100ul
