BAF60a (BRG1-associated factor 60A), also known as SMARCD1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1), Rsc6p or CRACD1, is a 476 amino acid protein that localizes to the nucleus and contains one SWIB domain.
Expressed ubiquitously with notable expression in liver, brain, muscle, lung, kidney, pancreas and placenta, BAF60a functions as a component of the BAF complex and, in conjunction with a variety of other proteins, plays an essential role in chromatin remodeling.
In addition, BAF60a influences vitamin D-mediated transcriptional activity and is thought to provide a link between the vitamin D receptor (VDR) and SWI/SNF chromatin remodeling complexes.
Multiple isoforms of BAF60a exist due to alternative splicing events.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of SMARCD1. Species Crossreactivity: Human, mouse, rat
