Smarcad1 (SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1), also known as ETL1 or HEL1, is a 1,026 amino acid nuclear protein suggested to function as an ATPdependent DNA helicase.
A member of the SNF2/RAD54 helicase family, Smarcad1 undergoes post-translational phosphorylation by either ATM or ATR and contains one helicase C-terminal domain, a helicase ATP-binding domain and two CUE domains.
Existing as two alternatively spliced isoforms, Smarcad1 is encoded by a gene that maps to human chromosome 4, which represents ~6% of the human genome, contains nearly 900 genes and is associated with Huntington’s disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of SMARCAD1. Species Crossreactivity: Human
