ZIP9 (Zinc transporter ZIP9, Solute carrier family 39 member 9) is a multi-pass (seven transmembrane regions) membrane protein that belongs to the ZIP transporter (TC 2.A.5) family.
Zinc transporters all have transmembrane domains, and are encoded by two SLC (solute-linked carrier) gene families: ZnT (SLC30) and Zip (SLC39).
There are at least 9 ZnT and 15 Zip transporters in human cells.
Zip transporters are believed to increase intracellular zinc by promoting zinc uptake.
This may be facilitated by vesicles within the cell that release release into the cytoplasm.
Zip and ZnT transporter families exhibit tissue-specific expression and respond differently to zinc deficiency and excess.
ZIP9 has been shown to localize to the trans-Golgi network regardless of zinc presence.
ZIP9 is believed to function as a zinc homeostasis regulator acting in the secretory pathway.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of SLC39A9. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 150-195 of Human SLC39A9.
