The SLC26 family is comprised of sulfate/anion transporters that are well conserved in both their genomic and protein structures, yet have markedly different tissue expression patterns.
Members of the SLC26 family can mediate the electroneutral exchange of Cl- for HCO3- across the plasma membrane of mammalian cells.
SLC26A2 (solute carrier family 26, member 2), also known as DTD, EDM4, DTDST, MST153, D5S1708 or MSTP157, is a 739 amino acid diastrophic dysplasia sulfate transporter belonging to the SLC26A/SulP transporter family.
Ubiquitously expressed, SLC26A2 may play a role in endochondral bone formation.
SLC26A2 is a transmembrane glycoprotein implicated in the pathogenesis of several human chondrodysplasias and is critical for sulfation of proteoglycans and matrix organization in cartilage.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of SLC26A2. Species Crossreactivity: Human