SLC25A11 (Solute carrier family 25 member 11), also known as Mitochondrial 2-oxoglutarate/malate carrier protein, is a 314 amino acid multi-pass transmembrane protein belonging to the mitochondrial carrier protein family.
As an oxoglutarate/malate carrier, SLC25A11 transports 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for dicarboxylic acids and malate.
SLC25A11 also participates in other important metabolic processes, such as the oxoglutarate/isocitrate shuttle and the malate-aspartate shuttle, as well as in nitrogen metabolism and in gluconeogenesis from lactate.
SLC25A11 contains 3 solcar repeats, which is typical of substrate carrier proteins involved in energy transfer.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of SLC25A11. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to the 174-219 of Human SLC25A11.
