NCKX1, also designated solute carrier family 24, member 1 (SLC24A1) or sodium/calcium/potassium exchanger 1, belongs to a family of potassium-dependent sodium/calcium exchangers.
Members of this group of proteins contain two large hydrophilic loops and two sets of multiple transmembrane-spanning segments.
One intron in the 5' untranslated region and eight within the coding region of the NCKX1 gene have been identified; exon length varies from 54 to 2,037 bp.
Human NCKX1 encodes a protein of 1,081 amino acids that shows 64% overall identity with the cow protein.
The two sets of presumed transmembrane domains and their short connecting loops show 94% identity with that of the cow, while the extracellular loop at the amino terminus is only 59% identical.
Applications:Suitable for use in Western Blot, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunocytochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of SLC24A1. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 198-243 of Human SLC24A1.
