SHB is an adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components.
It may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling.
It may also play a role in T cell antigen receptor/TCR signaling, interleukin 2 signaling, apoptosis and neuronal cells differentiation by mediating basic FGF and NGF-induced signaling cascades, and may also regulate IRS1 and IRS2 signaling in insulin producing cells.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of Shb. Species Crossreactivity: Human, mouse
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to amino acids 208-261 of Human Shb.
