This gene encodes a member of the serpin superfamily of serine proteinase inhibitors.
The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone.
Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis.
Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes.
Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of SERPINH1. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant full length Human SERPINH1.
Shelf Life：1year
Swiss Prot Number：P50454
EU Commodity Code：30021010
商品名：SERPINH1 (47kD Heat Shock Protein, 47kD Heat Shock Protein Precursor, Arsenic transactivated Protein 3, Arsenic-transactivated Protein 3, AsTP 3, AsTP3, CBP 1, CBP 2, CBP1, CBP2, Cell Proliferation-inducing Gene 14 Protein, Collagen Binding Protein 1, Collagen Binding Protein 2, Collagen Binding Protein, Collagen-Binding Protein 2, Collagen-Binding Protein, Colligen, Colligin 1, Colligin 2, Colligin, colligin-1, colligin-2, gp46, Heat Shock Protein 47, Heat-Shock Protein 47, HGNC 1547, Hsp 47, J6, OI10, PIG 14, PIG14, PPROM, Proliferation inducing Gene 14, Proliferation inducing Gene 14 Protein, RA A47, RA-A47, Rheumatoid arthritis Antigen A 47, rheumatoid arthritis Antigen A-47, Rheumatoid arthritis Related Antigen RA A47, Rheumatoid arthritis-Related Antigen RA-A47, Serine (or cysteine) Proteinase Inhibitor, clade H (Heat Shock Protein 47), Member 1, (collagen Binding Protein 1), Serine (or cysteine) Proteinase Inhibitor, clade H (Heat Shock Protein 47), Member 2, (collagen-Binding Protein 2), Serine or cysteine Proteinase Inhibitor clade H Member 1, Serine or cysteine Proteinase Inhibitor clade H Member 2, SERPH_HUMAN, Serpin H1, Serpin peptidase Inhibitor clade H Member 1, serpin peptidase Inhibitor, clade H (Heat Shock Protein 47), Member 1, (collagen Binding Protein 1), Serpin peptidase Inhibitor, clade H, Member 1, SERPINH1, SERPINH2,) 50ul
