The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class.
Polymorphisms in this protein appear to be tissue specific and influence protease targeting.
Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease.
Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
[provided by RefSeq, Jul 2008]
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of SERPINA3. Species Crossreactivity: Human
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant full length Human SERPINA3.
Shelf Life:1year
Swiss Prot Number:P01011
EU Commodity Code:30021010
商品名:SERPINA3 (SERPINA3, AACT, AACT_HUMAN, ACT, Alpha 1 Antichymotrypsin 1, Alpha 1 Antichymotrypsin 2, Alpha 1 Antichymotrypsin 3, Alpha 1 Antitrypsin Deficiency, Alpha-1-antichymotrypsin His-Pro-less, Anti Elastase, Antichymotrypsin, Cell Growth inhibiting Gene 24/25 Protein, Cell Growth-inhibiting Gene 24/25 Protein, Clade A (Alpha 1 AntiProteinase Antitrypsin), GIG24, GIG25, Growth inhibiting Protein 24, Growth inhibiting Protein 25, MGC88254, PI1, Protease Inhibitor 1, Serine (or Cysteine) Proteinase Inhibitor, Serine (or cysteine) Proteinase Inhibitor clade A (alpha 1 antiProteinase, antitrypsin) Member 3, Serine (or cysteine) Proteinase Inhibitor clade A Member 3, Serine Proteinase Inhibitor clade A Member 3, Serpin A3, Serpin peptidase Inhibitor clade A (alpha 1 antiProteinase antitrypsin) Member 3, SERPINA1, SERPINA2, SERPINA3,) 50ul