Septins play an important role in vesicle trafficking, apoptosis, cytoskeleton remodeling, infection, neurodegeneration, neoplasia and cytokinesis.
Septin 8 is a 508 amino acid protein that is expressed in the brain, cardiovascular regions, prostate, testis and ovary.
Septin 8 interacts with both Septin 5 and cell division cycle related-1 (CDCrel-1).
Septin 8 may play an important role in the functional regulation of hPFTAIRE1, a member of the Cdc2-related kinase family that is localized in cytoplasm.
Septin 8, Septin 4 and Septin 5 surround alpha-granules, implicating these three septins as components of the septin complex in platelets and contributing to platelet biology.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of Septin 8. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 178-220 of Human Septin 8.
