Sterol carrier protein 2 (SCP2), also designated nonspecific lipid-transfer protein, mitochondrial precursor, is involved in the non-specific transfer of intracellular sterol and lipid molecules between membranes.
A member of the thiolase family, SCP2 may also be involved in regulating steriodogenesis in fibroblasts, peroxisomes, liver and placenta.
In the liver it is a cytoplasmic protein but in steroidogenic tissues it localizes with mitochondria.
Isoform SCPx is associated with the peroxisome.
SCP2 is associated with Zellweger syndrome (cerebro-hepatic-renal syndrome), characterized by peroxisome deficiency and an impairment in plasmalogen and bile acid synthesis.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:500-1:2000Immunohistochemistry (Paraffin): 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography
Form：Supplied as a liquid PBS, pH 7.2, 0.02% sodium azide, 50% glycerol
Specificity：Recognizes endogenous levels of human SCP2. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Full-length recombinant protein corresponding to human SCP2
