84-2393-25　［取扱停止］SCARB2 (Lysosome Membrane Protein 2, 85kD lysosomal Membrane sialoglycoProtein, LGP85, CD36 Antigen-like 2, Lysosome Membrane Protein II, LIMP II, Scavenger Receptor class B Member 2, CD36, SCARB2, CD36L2, LIMP2, LIMPII) 100ul　225690

特徴

• Lysosomes are intracytoplasmic organelles that are found within leukocytes (granulocytes, neutrophils, basophils and eosinophils) and function as storage granules for small particles.
• Lysosomes actively support subcellular protein degradation mechanisms through fusion with cellular organelles such as phagocytic vacuoles and the plasma membrane.
• Lysosome fusion to the plasma membrane, known as exocytosis, releases the contents of the vesicle into the extracellular environment.
• The lysosomal integral membrane proteins I–III, known as LIMP-I, LIMP-II and LIMP-III, localize from the trans-Golgi network to lysosomes via an AP-3-dependent pathway that may involve AP-1 and Clathrin.
• LIMP I-III are protein markers for the lysosome organelle.
• These markers are exceptionally useful for microscopy studies, cellular fractionation validation and studies pertaining to protein trafficking through the secretory pathway.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.