84-2393-22　［取扱停止］SCARB1 (CD36 AND LIMPII ANALOGOUS 1, CD36, CD36 Antigen like 1, CD36 Antigen-like 1, CD36L1, CLA 1, CLA-1, CLA1, Collagen Type I Receptor, MGC138242, SCARB1, Scavebger Receptor Class B Member 1, Scavenger Receptor class B Member 1, Scavenger Receptor Class B Type 1, SCRB1, SR BI, SR-BI, SRB1, SRBI, Thrombospondin Receptor like 1, thrombospondin Receptor-like 1) 50ul　225689

特徴

• The macrophage class A scavenger receptors (SR-A) type I and II mediate the uptake of modified low density lipoprotein (LDL), while the scavenger receptor class B type 1 (SR-B1) mediates the selective uptake of cholesterol and cholesterol esters (CE) from HDLs into cells.
• SREC, Ox-LDL-R1, SR-A and SR-B1 may all be involved in the early development of atherosclerosis.
• SR-B1, an integral membrane protein, acts as a receptor for various ligands, including apoptotic cells, cholesterol ester, phospholipids, lipoproteins and phosphatidyl-serine.
• SR-B1, which may be involved in phagocytosis of apoptotic cells, enables the movement of cholesterol between the cell surface and extracellular donors and acceptors.
• Although it is widely expressed, SR-B1 localizes primarily to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.