SCAND1 (SCAN domain containing 1), also known as RAZ1 or SDP1, is a nuclear protein that may play a role in the mechanism of transcription regulation.
It is widely expressed with highest levels of expression found in kidney, thyroid, liver, prostate and testis.
SCAND1 contains one SCAN box domain and, unlike the majority of other SCAN domain containing proteins, it does not contain a zinc finger motif.
The SCAN box domain is a conserved leucine rich motif, ~60 amino acids in length, that participates in proteinprotein interactions.
SCAND1 interacts with ZNF38, ZNF191 and MZF-1.
It also interacts with ZNF202 and PPARγ, suggesting that it plays a role in the transcriptional regulation of genes that are involved in energy homeostasis and lipid metabolism.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of SCAND1. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 50-100 of Human SCAND1.
