84-2392-93　［取扱停止］SAA1 (Amyloid fibril Protein AA, Amyloid fibrils, Amyloid Protein A, Fibrils, MGC111216, OC, PIG 4, PIG4, SAA 1, SAA 2, SAA, SAA, SAA1, SAA2, Serum Amyloid A Protein Precursor, Serum Amyloid A1 Isoform 1, Serum Amyloid A1 Isoform 2, Serum Amyloid Protein A(4-101), TP53I4, Tumor Protein p53 inducible Protein 4) 50ul　225674

特徴

• The serum amyloid A (SAA) family of proteins is encoded by multiple genes, which display allelic variation and a high degree of homology in mammals.
• The four members of the SAA gene family are clustered on human chromosome 11p15.1.
• Three SAA genes are differentially expressed and encode small apolipoproteins.
• SAA1 and SAA2 encode the acute phase SAAs (A-SAAs), and SAA4 encodes the constitutively expressed SAA (C-SAA).
• A fourth locus, SAA3 is a pseudogene that contains two C/EBP-binding sites and a third site, which interacts with SAA3 enhancer factor.
• Human SAA proteins are a group of apolipoproteins found predominantly in the high-density lipoprotein (HDL) fraction of plasma.
• SAA is a major acute-phase protein and precursor to amyloid A protein, which is the major constituent of the fibril deposits of reactive amyloidosis.
• SAA is secreted in large amounts by the liver during microbial infections or inflammatory diseases.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.