84-2392-21　［取扱停止］RPS6KA3 (90kD Ribosomal Protein S6 Kinase 3, CLS, HU 3, HU2, HU3, Insulin stimulated Protein Kinase 1, Insulin-stimulated Protein Kinase 1, ISPK-1, ISPK1, KS6A3_HUMAN, MAP Kinase Activated Protein Kinase 1b, MAP Kinase-Activated Protein Kinase 1b, MAPK Activated Protein Kinase 1b, MAPK-Activated Protein Kinase 1b, MAPKAP Kinase 1b, MAPKAPK 1b, MAPKAPK-1b, MAPKAPK1 ...　225637

特徴

• The family of ribosomal S6 kinases (Rsks), designated Rsk-1 (or MAPKAP kinase-1), Rsk-2 and Rsk-3, are intracellular serine/threonine kinases that are important signaling intermediates in response to a broad range of ligand activated receptor tyrosine kinases.
• A unique feature common to the members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains.
• An additional Rsk protein, Rsk-4, shows a high level of homology to the three previously isolated members of the human Rsk family.
• Rsk-4 is most abundantly expressed in brain and kidney and plays a role in normal neuronal development.
• The family of ribosomal S6 kinases includes p70 S6 kinase and p70 S6 kinase beta, which are thought to have similar regulatory functions.
• MSK1 (also designated RLPK) is a novel Rsk-related protein, which, like the p90 Rsk family members, contains two non-identical complete kinase catalytic domains.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.