RNA polymerases transcribe nuclear genes for ribosomal RNA and are integral components of ribosomal biogenesis.
RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA.
RNA polymerase II (Pol II) synthesizes mRNA.
RNA polymerase III (Pol III) transcribes class III genes, encoding a number of small ribosomal RNA molecules including tRNA and 5S rRNA.
RPAP1 (RNA polymerase II associated protein 1) is a 1,393 amino acid nuclear protein that is thought to connect Pol II to acetylated Histone H3 and regulators of protein complex formation.
A member of the RPAP1 family, RPAP1 exists as three alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 15q15.1.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of RPAP1. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to residues in Human RPAP1.
