Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation.
The protein encoded by this gene is one of the PcG proteins.
It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2).
Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development.
This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of RNF2. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant full length Human RNF2.
Shelf Life：1year
Swiss Prot Number：Q99496
EU Commodity Code：30021010
商品名：RNF2 (BAP 1, BAP1, DING, DinG Protein, E3 Ubiquitin Protein Ligase RING 2, E3 Ubiquitin Protein Ligase RING2, E3 Ubiquitin-Protein Ligase RING2, HIP2 interacting Protein 3, HIP2-interacting Protein 3, HIPI 3, HIPI3, Huntingtin interacting Protein 2 interacting Protein 3, Huntingtin-interacting Protein 2-interacting Protein 3, OTTHUMP00000060668, Polycomb M33 interacting Protein Ring 1B, Polycomb M33 interacting Protein Ring1B, Protein DinG, RING 1B, RING 2, RING Finger Protein 1B, RING Finger Protein 2, RING Finger Protein BAP 1, RING Finger Protein BAP-1, RING Finger Protein BAP1, RING1b, RING2_HUMAN, RNF 2, Rnf2,) 50ul
