84-2390-57　［取扱停止］RHOQ (Rho-Related GTP-Binding Protein RhoQ , Ras-like Protein TC10, Ras-like Protein Family Member 7A, RHOQ, ARHQ, RASL7A, TC10) 50ul　225555

特徴

• tc10 is a small GTP-binding protein that is induced during nerve injury, where it cooperates with other Rho family members to facilitate nerve regeneration and, in particular, neurite elongation.
• tc10 is located predominantly in the plasma membrane, a property that depends both on its post-translational prenylation and on its ability to bind and hydrolyze GTP.
• tc10 colocalizes to actin filaments and interacts with the actin-binding and filament-forming protein, profilin.
• tc10 functions to regulate cellular signaling to the actin cytoskeleton and processes associated with cell growth.
• tc10 also interacts with a similar subset of effectors for Cdc42 and is regulated differentially by p50Rho GTPase-activating protein.
• Activated tc10 interacts with a variety of putative Rho family effectors, stimulates JNK, and induces filopodial formation.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.