84-2389-89　［取扱停止］Renin Receptor (ATPase H(+)-transporting lysosomal accessory Protein 2, ATPase H(+)-transporting lysosomal-interacting Protein 2, ER-localized Type I Transmembrane adaptor, Embryonic liver Differentiation Factor 10 N14F, Renin/prorenin Receptor, Vacuolar ATP Synthase Membrane sector-Associated Protein M8-9, ATP6M8-9, V-ATPase M8.9 Subunit, ATP6AP2, ATP6IP2, CAPER, ...　225520

特徴

• The Renin Receptor, also known as ATP6AP2 (ATPase H+-transporting lysosomal accessory protein 2), ATP6IP2 (ATPase H+-transporting lysosomal-interacting protein 2), CAPER or M8-9, is an ATPase-associated protein that functions as a Renin and prorenin cellular receptor.
• Expressed in the brain, heart, liver, kidney, placenta and pancreas, the Renin Receptor functions to activate ERK 1 and ERK 2, thereby mediating Renin-dependent cellular responses.
• The Renin Receptor has a subunit that associates with the transmembrane domain of V-type ATPases and interacts with Renin.
• These interactions increase the catalytic activity of Renin in the Renin-Angiotensin system (RAS), thus upregulating the conversion of angiotensinogen to Angiotensin.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.