84-2389-73　［取扱停止］REG3A (Regenerating Islet-derived Protein 3-alpha, REG-3-alpha, REG 3alpha, REG-3alpha, REG3alpha, Hepatointestinal pancreatic Protein, HIP/PAP, Human proIslet peptide, Pancreatitis-Associated Protein 1, Regenerating Islet-derived Protein III-alpha, Reg III-alpha, Regenerating Islet-derived Protein 3-alpha 16.5kD form, Regenerating Islet-derived Protein 3-alpha 15 ...　225512

特徴

• The regeneration (REG) family consists of secretory proteins involved in liver, pancreatic, gastric and intestinal cell proliferation or differentiation.
• Members of the REG family are divided into four subclasses, designated types I, II, III and IV.
• They have been implicated in the regulation of cell growth, tumorigenesis and the progression of cancer.
• Specifically, increased expression of Reg IIIa results in pancreatic inflammation and liver carcinogenesis.
• Reg IIIa, also de-signated pancreatitis-associated protein, localizes to the apical region of pancreatic acinar cells and is similar to the C-type lectin superfamily.
• The Reg IIIa protein is mainly expressed in the intestine, with lower expression detected in healthy pancreas.
• It is also detected in pancreatic juice as a result of pancreatic inflammation.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.