84-2388-71 [取扱停止]RAN (Androgen Receptor Associated Protein 24, Androgen Receptor-Associated Protein 24, ARA 24, ARA24, Gsp1, GTP Binding Nuclear Protein RAN, GTP-Binding Nuclear Protein Ran, GTPase Ran, LPS, ran, RAN Member RAS Oncogene Family, RAN, Ras like Protein TC4, Ras Related Nuclear Protein, Ras-like Protein TC4, Ras-Related Nuclear Protein, RASL2 8, TC 4, TC4) 50ul 225461
84-2388-71 [取扱停止]RAN (Androgen Receptor Associated Protein 24, Androgen Receptor-Associated Protein 24, ARA 24, ARA24, Gsp1, GTP Binding Nuclear Protein RAN, GTP-Binding Nuclear Protein Ran, GTPase Ran, LPS, ran, RAN Member RAS Oncogene Family, RAN, Ras like Protein TC4, Ras Related Nuclear Protein, Ras-like Protein TC4, Ras-Related Nuclear Protein, RASL2 8, TC 4, TC4) 50ul 225461
GTP-binding protein involved in nucleocytoplasmic transport.
Required for the import of protein into the nucleus and also for RNA export.
Involved in chromatin condensation and control of cell cycle.
The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.
Enhances AR-mediated transactivation.
Transactivation decreases as the poly-Gln length within AR increases.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of RAN. Species Crossreactivity: Human, mouse, rat