84-2387-87　［取扱停止］Rad51B (DNA Repair Protein RAD51 Homolog 2, R51H2, RAD51 Homolog B, Rad51B, RAD51-like Protein 1, RAD51B, RAD51L1, REC2) 100ul　225417

特徴

• The DNA repair proteins Rad50, Rad51A-D, Rad52 and Rad54 A and B are key components of the double-strand break repair pathway (DSBR).
• The process of homologous recombination is a major DNA repair pathway that operates on DNA double-strand breaks to promote error-free repair.
• Human Rad51 protein assembles on a DNA molecule through cooperative binding and forms a long filament for homologous recombination.
• In addition to Rad51 protein, five paralogs have been identified in vertebrates, Rad51B, Rad51C, Rad51D, Xrcc2 and Xrcc3.
• Rad51B is a widely expressed protein that is involved in the repair of double-stranded DNA breaks that can arise during DNA replication.
• It can form a dimer with Rad51C and this complex shows single-stranded DNAdependent ATPase activity.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.