Rabr, also known as AGFG2 (Arf-GAP domain and FG repeats-containing protein 2), is a 481 amino acid member of the HIV-1 REV binding protein (HRB) family and has one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs.
Rabr shares 46% identity with Rab.
Both Rab and Rabr contain a zinc finger region near the N terminus, several phe-gly (FG) motifs, which is characteristic of nucleoporin-like proteins, and four NPF motifs located in the C-terminal region.
Rabr interacts with Eps15 homology (EH) domains and plays a role in the REV export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity:Recognizes endogenous levels of Rabr. Species Crossreactivity: Human, mouse
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to amino acids 101-150 of Human Rabr.